Cosmelan Peel

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Cosmelan Peel

Di-Or Skin & Rejuvenation Clinic is a registered distributor / stockist / clinic providing the Mesoestetic Cosmelan® Depigmentation Peel procedure using genuine Mesoestetic Cosmelan® products and equipment.

Cosmelan® Peel Treatment

Aesthetic depigmentation treatment for professional use: cosmelan®

Skin problems

Pigmentation concerns are a growing, global issue; they affect more than 90% of adults over the age of 50. They are a significant issue because of their unattractive appearance and negative psychological and emotional impact, affecting quality of life.

Skin hyperpigmentation is caused by abnormal production of melanin, the pigment responsible for skin colour, and is a consequence of uncontrolled, localized overproduction of melanin by the melanocytes, causing irregular skin coloration and dark spots.

Cosmelan Treatment

Cosmelan® is a professional depigmentation method which has an intensive corrective effect on skin hyperpigmentations, reducing the dark spots that occur due to sun exposure, acne, aging, and hormone fluctuation whilst regulating the overproduction of melanin in the melanocytes, inhibiting and controlling the appearance of new dark spots.

Its efficacy is based on its double mechanism of action that on the one part has a corrective effect, eliminating the hyperpigmentation and, on the other, a regulating effect, controlling the overproduction of melanin and in this way preventing the appearance of new spots in the long term.



Cosmelan® is the world’s leading professional depigmenting method. Cosmelan® 2 is the topical anti-spot cream for home use. Maintains the results obtained with the professional treatment and prevents the appearance of new skin alterations.

Cosmelan® is a complete method that involves a single session, which can be performed at beauty clinics and dermatological or aesthetic medicine practices and a home maintenance treatment.

The session entails the professional applying the Cosmelan® 1 face mask which is then left to work for 8 to 12 hours, according to the phototype and sensitivity of the skin to be treated. After this time has elapsed the mask is removed at home.

48 hours later, the follow-up phase in your home is started with the application of the Cosmelan® 2, hydra-vital factor K cream and the moisturizing sun protection SPF50+. This follow-up phase is carried out for 7 months to achieve an optimal result and prevent the reappearance of spots. 

Cosmelan® Skin Concerns & Solutions

Reduces dark spots and Hyperpigmentation The Irregular, flat, asymmetric spots of dark pigmentation, either localized or dispersed that appear on facial skin, abdomen, legs, hands, breasts and nipple area. Dull skin, dry areas, dark spots, blemishes can be significantly reduced with the peel.

Effective in the treatment of Melasma and Cholasma Discoloration due to Melasma (brown to grey patches over the bridge of the nose, cheeks, chin, and elsewhere on the face and body; often the result of hormonal changes. Chloasma (similar to Melasma, referred to as the Mask of Pregnancy) can be eliminated with the Cosmelan.

Improves Acne and Freckles Cosmelan balances the skin’s oil production to improve acne and acne scars as well as improving the appearance of freckles.

Suitable for All Skin Types Cosmelan Depigmentation Peel is suitable for all skin types and tones.

Ideal Patient Understands the Cosmelan Chemical Peel process and the requirements for follow up care. They should be in overall good health, and hold realistic expectations for their results.

The Cosmelan Depigmentation Peel has minimal pain, minimal side effects and quick results!


Di-Or Clinic schedules a private consultation with each patient, before beginning any aesthetic treatment. During this time your Skin Therapist will perform an evaluation of skin’s tone, texture, and facial anatomy and discuss your medical history, as well as your aesthetic goals.

Cosmelan® Depigmentation Peel Procedure

The Cosmelan® Method Protocol

Two Step Process

Step 1: Application of the stimulating mask

  • Skin is cleansed.
  • Cosmelan 1 mask is applied in a thick layer to clean dry skin through a gentle massage
  • Mask may lightly sting on initial application but this will quickly subside.
  • Depending on the area treated, the mask needs to remain on between 6-12 hours.
  • Instructions on how to remove the mask at home and an after-care kit will be provided.

Step 2 Application of Cosmelan products for Home Aftercare

  • The Cosmelan mask is removed at home with a gentle, neutral cleanser.
  • Mesoestetic Hydra-Vital Factor K is applied immediately after the mask has been removed to comfort the skin and protect moisture.
  • Skin peeling process begins within 2-3 days after the mask’s application.
  • Cosmelan 2 cream should be applied 2-3 times a day for 14 days.
  • After 14 days Cosmelan 2 can be applied once daily.
  • Since cosmelan 2 forms part of an integral treatment it is recommended to consult with our professional skin therapist on the precise instructions of the “cosmelan method protocol”.

Cosmelan® Peel Effects

Continuous depigmenting: 48 hours after removing the cosmelan 1 mask, it is necessary to continue with the daily routine to supplement the corrective depigmenting action of the method and to regulate overproduction of melanin inside the melanocyte.

Control of hyperpigmentation: At this point, it is important to treat the root cause of the blemish, controlling the overproduction of melanin by constant regulation of the melanocyte. This controls both intra- and intercellular melanin production and prevents repigmentation. Apply cosmelan 2 morning and night, followed by hydra-vital factor k, and moisturizing sun protection SPF 50+ during the day. In case of sun exposure, reapply UV protection at midday.

Control of reappearance: The tendency to develop dark spots is an ongoing risk. During this control phase, the reappearance of the treated spots and the formation of new ones is prevented, prolonging the results of the method for longer. Apply cosmelan 2 at night, followed by hydra-vital factor k. During the day, apply moisturizing sun protection SPF 50+ and reapply in cases of direct sun exposure.

Sun protection: Once the method is complete, we strongly recommend continuous use of sun protection as a permanent cosmetic treatment

Cosmelan® Peel Results

Initially you will notice skin blemishes begin to fade and a brighter complexion emerging. Within a couple of weeks, your skin will become more radiant with a healthier glow. The full benefits of the Cosmelan Peel will be seen within 4-5 weeks.

The Cosmelan Peel lasts for many months and it is imperative to follow the home aftercare process to obtain optimum results. Your skin will be sensitive the first two weeks after treatment and you should avoid sun exposure. Apply a full spectrum sunscreen at all times.

Minimal side effects

May include light to moderate redness and discomfort, similar to a sunburn. It is common for your skin to feel tight or itchy. In more serious complications scarring may occur. Di-Or Clinic is a trusted aesthetic practice and as such it will reduce your chance for any negative side effects from the Cosmelan treatment.

Mesoestetic Cosmelan® Depigmentation treatment starts from $500 to $1,500.